Mathematical Modeling and Yeast Oxidative Stress Project @ VBI
This systems biology project is a collaboration between the Laubenbacher, Mendes and Shulaev labs at the Virginia Bioinformatics Institute. Our aim is to develop new techniques to construct integrative mathematical models of biological systems, and we will focus on the yeast Saccharomyces cerevisiae oxidative stress response as an example.
This integrative project consists of two major areas:
Modeling: The Laubenbacher group is developing methods to create top-down models of biological systems using discrete mathematics . The Mendes group is developing methods based on ((Continuous Methods|(continuous) nonlinear dynamics)) to create top-down models of biological systems. Both methods are being developed with simulated data and with the results of our own yeast systems biology experiments (below).
This project is funded by the NIGMS under grant number RO1 GM068947-01
We are part of the Yeast Systems Biology Network